验证数据展示
产品信息
25690-1-PBS targets DPYD in WB, Indirect ELISA applications and shows reactivity with mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | mouse |
免疫原 | DPYD fusion protein Ag20885 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | dihydropyrimidine dehydrogenase |
别名 | |
计算分子量 | 1025 aa, 111 kDa |
观测分子量 | 111 kDa |
GenBank蛋白编号 | BC008379 |
基因名称 | DPYD |
Gene ID (NCBI) | 1806 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q12882 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.