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DOK5 Polyclonal antibody

DOK5 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 11948-1-AP

Print datasheet

Synonyms

C20orf180, docking protein 5, DOK5, IRS 6, IRS6

验证数据展示

  • WB analysis of mouse liver using 11948-1-AP

    WB analysis of mouse liver using 11948-1-AP

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 11948-1-AP (DOK5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse liver tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11948-1-AP targets DOK5 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA
Tested Reactivity human, mouse, rat
Immunogen DOK5 fusion protein Ag2615 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name docking protein 5
Synonyms C20orf180, docking protein 5, DOK5, IRS 6, IRS6
Calculated Molecular Weight 306 aa, 35 kDa
Observed Molecular Weight 35 kDa
GenBank Accession NumberBC008992
Gene Symbol DOK5
Gene ID (NCBI) 55816
RRIDAB_10665550
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9P104
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

DOK5 belongs to the docking family of proteins that contain tandem pleckstrin homology-phosphotyrosine binding (PH-PTB) domains at their amino termini (PMID: 19909370). DOK proteins are also known as INS receptor substrates (IRS) and serve as substrates for INS and INS-like growth factor (PMID: 12730241 ) as well as various protein tyrosine kinases (PMID: 16647839). DOK5 functions as a specific signal transduction molecule and plays an important role in cellular differentiation. DOK5 is upregulated in systemic Sclerosis and Associated with IGFBP-5-Induced fibrosis (PMID: 24551065).

实验方案

Product Specific Protocols
WB protocol for DOK5 antibody 11948-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols