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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 29984-1-AP (same clone as 29984-1-PBS)

    WB analysis using 29984-1-AP (same clone as 29984-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29984-1-AP (DICER1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29984-1-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 29984-1-AP (same clone as 29984-1-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 29984-1-AP (same clone as 29984-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 29984-1-AP (DICER1 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29984-1-PBS in a different storage buffer formulation.

DICER1 Polyclonal antibody, PBS Only

DICER1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 29984-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

HERNA, Helicase MOI, Endoribonuclease Dicer, EC:3.1.26.3, DICER

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

29984-1-PBS targets DICER1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 DICER1 fusion protein Ag30368 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 dicer 1, ribonuclease type III
别名 HERNA, Helicase MOI, Endoribonuclease Dicer, EC:3.1.26.3, DICER
计算分子量 219 kDa
观测分子量90 kDa, 220-250 kDa
GenBank蛋白编号NM_030621
基因名称 DICER1
Gene ID (NCBI) 23405
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UPY3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DICER1 functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. DICER1 cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, and producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation.