验证数据展示
产品信息
67718-1-Ig targets DHX58 in ELISA applications and shows reactivity with Human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | Human |
| 免疫原 | DHX58 fusion protein Ag30382 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | DEXH (Asp-Glu-X-His) box polypeptide 58 |
| 别名 | D11LGP2, D11lgp2e, DHX58, LGP2, Protein D11Lgp2 homolog, RIG I like receptor LGP2, RLR |
| 计算分子量 | 678 aa, 77 kDa |
| GenBank蛋白编号 | BC014949 |
| 基因名称 | DHX58 |
| Gene ID (NCBI) | 79132 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q96C10 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
DHX58(Probable ATP-dependent RNA helicase DHX58) is also named as D11LGP2E, LGP2 and belongs to the RLR subfamily. DHX58, originally identified as a highly expressed gene in mammary tumors, is another cytoplasmic DEX(D/H)-box helicase that can recognize RNA(PMID: 18411269). It acts as a positive, but not negative, regulator of RIG-I-and MDA5-dependent recognition of RNA virus infection and plays a pivotal role in antiviral responses in vivo(PMID:20080593).