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Cyclo(L-Phe-L-Pro)

Cyclo(L-Phe-L-Pro) 具有广谱抗菌和抗真菌活性。 Cyclo(L-Phe-L-Pro) 对耐甲氧西林金黄色葡萄球菌和棉子肠球菌具有活性。

CAS号

3705-26-8

分子式

C14H16N2O2

主要靶点

Antibacterial|Free radical scavengers|Antifungal|COX

仅限科研使用

Cat No : CM18759

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Synonyms

验证数据展示

  • CAS No.: 3705-26-8

    Cyclo(L-Phe-L-Pro)
    CAS#: 3705-26-8

产品信息

Cyclo(L-Phe-L-Pro) shows broad-spectrum antibacterial and antifungal activities. Cyclo(L-Phe-L-Pro) exhibits activity against methicillin-resistant S. aureus and Enterococcus raffinosus.

CAS号 3705-26-8
分子式 C14H16N2O2
主要靶点 Antibacterial|Free radical scavengers|Antifungal|COX
主要通路 神经科学|微生物学|免疫与炎症|氧化还原
分子量 244.29
纯度 98.14%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

体外活性

Cyclo(L-Phe-L-Pro) interferes with the activation of retinoic-acid-inducible gene-I and inhibits the production of IFN-β[2]. Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with an IC50 value of 24 µM for DPPH[3].

溶解度

DMSO:225.0 mg/mL (921.0 mM),Sonification is recommended.

参考文献

1.Katrin Ström, et al. Lactobacillus plantarum MiLAB 393 Produces the Antifungal Cyclic Dipeptides Cyclo(L-Phe-L-Pro) and Cyclo(L-Phe-trans-4-OH-L-Pro) and 3-Phenyllactic Acid. Appl Environ Microbiol. 2002 Sep;68(9):4322-7.
2.Wooseong Lee, et al. Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity. Nat Commun. 2018 Apr 23;9(1):1606.
3.Keyong Ho Lee, et al. Radioprotective effect of cyclo(L-phenylalanyl-L-prolyl) on irradiated rat lung. J Microbiol Biotechnol. 2008 Feb;18(2):369-76.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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