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Cyclandelate

CAS号

456-59-7

分子式

C17H24O3

主要靶点

Acyltransferase

仅限科研使用

Cat No : CM05492

Print datasheet

Synonyms

Cyclandelate|inhibit|3,5,5-Trimethylcyclohexyl mandelate|ACAT|BS572|BS-572|BS 572|Inhibitor|安脉生|环扁桃酯

验证数据展示

  • CAS No.: 456-59-7

    Cyclandelate
    CAS#: 456-59-7

产品信息

CAS号 456-59-7
分子式 C17H24O3
主要靶点 Acyltransferase
主要通路 代谢
分子量 276.37
纯度 99.21%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Cyclandelate|inhibit|3,5,5-Trimethylcyclohexyl mandelate|ACAT|BS572|BS-572|BS 572|Inhibitor|安脉生|环扁桃酯

体内活性

在血管平滑肌中,Cyclandelate通过钙离子通道拮抗作用,使周围血管扩张。Cyclandelate使芳香族和脂族酯水解,参与异生素的解毒以及酯类和酰胺类前药的活化,但对酰胺或脂肪酰基CoA酯无催化活性。

溶解度

DMSO:55 mg/mL (199 mM);Ethanol:51 mg/mL (184.5 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

参考文献

1.Middleton B, et al. Drugs, 1987, 33 Suppl 2:75-9.
2.Heffron F, et al. Biochem Pharmacol, 1990, 39(3), 575-580.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2