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Coumarin-3-carboxylic acid

Coumarin-3-carboxylic acid (3-Carboxycoumarin) 是一种合成香豆素的重要起始化合物。其中香豆素是具有多种生物活性的天然产物。它的镧系复合物对 K-562 细胞具有抗增殖活性。

CAS号

531-81-7

分子式

C10H6O4

主要靶点

VEGFR

仅限科研使用

Cat No : CM01510

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Synonyms

3-Carboxycoumarin|香豆素-3-羧酸

验证数据展示

  • CAS No.: 531-81-7

    Coumarin-3-carboxylic acid
    CAS#: 531-81-7

产品信息

The combination of Valproic acid with coumarin-3-carboxylic acid suppresses the proliferation and migration of lung cancer cells via EGFR/VEGFR2/c-Met-Akt-NF-κB signaling pathways; this combination may have a wide therapeutic and/or adjuvant therapeutic application in the treatment of lung cancer.

CAS号 531-81-7
分子式 C10H6O4
主要靶点 VEGFR
主要通路 蛋白酪氨酸激酶|血管生成
分子量 190.15
纯度 99.76%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 3-Carboxycoumarin|香豆素-3-羧酸

溶解度

DMSO:199.8 mM

参考文献

1.Xin Liu, et al. Enhanced suppression of proliferation and migration in highly-metastatic lung cancer cells by combination of valproic acid and coumarin-3-carboxylic acid and its molecular mechanisms of action. Cytotechnology. 2013 Aug; 65(4): 597–608.

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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