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Coenzyme A

CAS号

85-61-0

分子式

C21H36N7O16P3S

主要靶点

Endogenous Metabolite

仅限科研使用

Cat No : CM01658

Print datasheet

Synonyms

Endogenous Metabolite|fatty acid metabolism|EndogenousMetabolite|inhibit|Human Endogenous Metabolite|acyl group carrier|Coenzyme A|citric acid cycle|Inhibitor|metabolism|辅酶 A|ubiquitous essential cofactor

验证数据展示

  • CAS No.: 85-61-0

    Coenzyme A
    CAS#: 85-61-0

产品信息

CAS号 85-61-0
分子式 C21H36N7O16P3S
主要靶点 Endogenous Metabolite
主要通路 代谢
分子量 767.53
纯度 93.84%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Endogenous Metabolite|fatty acid metabolism|EndogenousMetabolite|inhibit|Human Endogenous Metabolite|acyl group carrier|Coenzyme A|citric acid cycle|Inhibitor|metabolism|辅酶 A|ubiquitous essential cofactor

体外活性

Coenzyme A与Peroxiredoxin 5 (Prdx5) 的共价结合彻底抑制了其过氧化物酶活性，但可以通过DTT还原逆转。包括癌症、糖尿病和神经退行性疾病在内的多种人类病理状态与CoA及其衍生物的异常生物合成和稳态失调有关。

溶解度

DMSO:50 mg/mL (65.14 mM)

参考文献

1.Bakovi? J, et al. A key metabolic integrator, coenzyme A, modulates the activity of peroxiredoxin 5 via covalent modification. Mol Cell Biochem. 2019 Aug 2.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2