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Ceapin-A7

Ceapin-A7 是内质网应激 ATF6α信号的选择性阻断剂(IC50:0.59 μM)，可用于探讨 ATF6α 促细胞活化的机制及其在病理环境中的作用。

CAS号

2323027-38-7

分子式

C20H12F6N4O3

主要靶点

Others

仅限科研使用

Cat No : CM03042

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Synonyms

验证数据展示

  • CAS No.: 2323027-38-7

    Ceapin-A7
    CAS#: 2323027-38-7

产品信息

Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings.

CAS号 2323027-38-7
分子式 C20H12F6N4O3
主要靶点 Others
主要通路 其他
分子量 470.32
纯度 99.73%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

靶点活性

ATF6α:0.59 μM

溶解度

DMSO:100 mg/mL (212.62 mM),Sonification is recommended.

参考文献

1.Ciara M Gallagher, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. eLife. 2016; 5: e11878.

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