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Carbimazole

CAS号

22232-54-8

分子式

C7H10N2O2S

主要靶点

Thyroid hormone receptor(THR)

仅限科研使用

Cat No : CM00138

Print datasheet

Synonyms

THR|Thyroid hormone receptor|Thyroid hormone receptor(THR)|Thyroid peroxidase|Thyroidhormonereceptor|Thyroidhormonereceptor(THR)|卡比马唑|卡比吗唑|Neomercazole|Inhibitor|methimazole|MMI|Graves' disease|inhibit|Carbimazol|Carbimazole|Athyromazole|antithyroid agent

验证数据展示

  • CAS No.: 22232-54-8

    Carbimazole
    CAS#: 22232-54-8

产品信息

CAS号 22232-54-8
分子式 C7H10N2O2S
主要靶点 Thyroid hormone receptor(THR)
主要通路 内分泌与激素
分子量 186.23
纯度 99.22%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 THR|Thyroid hormone receptor|Thyroid hormone receptor(THR)|Thyroid peroxidase|Thyroidhormonereceptor|Thyroidhormonereceptor(THR)|卡比马唑|卡比吗唑|Neomercazole|Inhibitor|methimazole|MMI|Graves' disease|inhibit|Carbimazol|Carbimazole|Athyromazole|antithyroid agent

体内活性

Carbimazole被人体吸收后转化为甲巯咪唑,产生抗甲状腺作用,作用于抗甲亢(过度产生甲状腺激素)和甲状腺毒症(甲状腺炎症)。

溶解度

Ethanol:12 mg/mL (64.44 mM);DMSO:60 mg/mL (322.18 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

参考文献

1.Taurog A, et al. Endocrinology, 1976, 98(4), 1031-1046.
2.Magnusson RP, et al. J Biol Chem, 1984, 259(1), 197-205.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2