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验证数据展示

  • WB analysis of A549 using 11235-2-AP (same clone as 11235-2-PBS)

    WB analysis of A549 using 11235-2-AP (same clone as 11235-2-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 11235-2-AP (CREB3L1,OASIS antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This batch of A549 cells lysate predominantly expressed the maturer form likely due to cell stage. This data was developed using the same antibody clone with 11235-2-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 11235-2-AP (same clone as 11235-2-PBS)

    IHC staining of human prostate cancer using 11235-2-AP (same clone as 11235-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 11235-2-AP (CREB3L1,OASIS antibody) at dilution of 1:50 (under 25x lens). This data was developed using the same antibody clone with 11235-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CREB3L1 antibody included
  • IF Staining of A549 using 11235-2-AP (same clone as 11235-2-PBS)

    IF Staining of A549 using 11235-2-AP (same clone as 11235-2-PBS)

    Immunofluorescent analysis of (10% Formaldehyde) fixed A549 cells using 11235-2-AP (CREB3L1,OASIS antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 11235-2-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

CREB3L1,OASIS Polyclonal antibody, PBS Only

CREB3L1,OASIS Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 11235-2-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CREB3L1 Ready-To-Use IHC Kit. CREB3L1 primary antibody included.

产品信息

11235-2-PBS targets CREB3L1,OASIS in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag1757

Product name: Recombinant human CREB3L1,OASIS protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 170-519 aa of BC015781

Sequence: PHQAPGEMTQLPVIKAEPLEVNQFLKVTPEDLVQMPPTPPSSHGSDSDGSQSPRSLPPSSPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETFTSENNELWKKVETLENANRTLLQQLQKLQTLVTNKISRPYKMAATQTGTCLMVAALCFVLVLGSLVPCLPEFSSGSQTVKEDPLAADGVYTASQMPSRSLLFYDDGAGLWEDGRSTLLPMEPPDGWEINPGGPAEQRPRDHLQHDHLDSTHETTKYLSEAWPKDGGNGTSPDFSHSKEWFHDRDLGPNTTIKLS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cAMP responsive element binding protein 3-like 1
别名
计算分子量 57 kDa
观测分子量 55-58 kDa and 84 kDa
GenBank蛋白编号BC015781
基因名称 CREB3L1/OASIS
Gene ID (NCBI) 90993
RRIDAB_2086042
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96BA8
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cyclic AMP-responsive element-binding protein 3-like protein 1(CREB3L1) belongs to a family of transcription factors that are synthesized as membrane-bound precursors in the endoplasmic reticulum (ER) and then transported to the Golgi where they are activated through regulated intramembrane proteolysis (RIP). Also it participates in ER-stress response in astrocytes in the central nervous system. It may has a role in gliosis, and involves in activation of transcription through box-B element but not CRE. CREB3L1 acts as a transcription repressor in proliferation of virus-infected cell. The full-length precursor form (approximately 84 kDa) of CREB3L1 and the matured form of CREB3L1 is 58 kDa. (PMID: 20668028)

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