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CPDA

CAS号

1415834-63-7

分子式

C20H15ClF2N2O2

主要靶点

Phosphatase

仅限科研使用

Cat No : CM05902

Print datasheet

Synonyms

inhibit|CPDA|SHIP2|Inhibitor|Phosphatase

验证数据展示

  • CAS No.: 1415834-63-7

    CPDA
    CAS#: 1415834-63-7

产品信息

CAS号 1415834-63-7
分子式 C20H15ClF2N2O2
主要靶点 Phosphatase
主要通路 代谢
分子量 388.8
纯度 98.34%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 inhibit|CPDA|SHIP2|Inhibitor|Phosphatase

体内活性

CPDA greatly improves abnormal glucose metabolism in diabetic animals. In db/db mice, CPDA improves abnormal glucose metabolism.

体外活性

CPDA enhances insulin signaling. CPDA was found to enhance in vitro insulin signaling through the Akt pathway more efficiently than the previously reported SHIP2 inhibitor AS1949490, and ameliorated abnormal glucose metabolism in diabetic (db/db) mice.

溶解度

DMSO:50 mg/mL (128.60 mM)

参考文献

1.Rational design and synthesis of 4-substituted 2-pyridin-2-ylamides with inhibitory effects on SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2). Eur J Med Chem. 2013 Apr;62:649-660.

The molarity calculator equation

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质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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