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验证数据展示

  • WB analysis of mouse heart using 12481-1-AP (same clone as 12481-1-PBS)

    WB analysis of mouse heart using 12481-1-AP (same clone as 12481-1-PBS)

    mouse heart tissue were subjected to SDS PAGE followed by western blot with 12481-1-AP (COQ6 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

  • WB analysis using 12481-1-AP (same clone as 12481-1-PBS)

    WB analysis using 12481-1-AP (same clone as 12481-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12481-1-AP (COQ6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse ovary using 12481-1-AP (same clone as 12481-1-PBS)

    IHC staining of mouse ovary using 12481-1-AP (same clone as 12481-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse ovary tissue slide using 12481-1-AP (COQ6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse ovary using 12481-1-AP (same clone as 12481-1-PBS)

    IHC staining of mouse ovary using 12481-1-AP (same clone as 12481-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse ovary tissue slide using 12481-1-AP (COQ6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

COQ6 Polyclonal antibody, PBS Only

COQ6 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 12481-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

12481-1-PBS targets COQ6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 COQ6 fusion protein Ag3164 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
别名
计算分子量 468 aa, 51 kDa
观测分子量 51 kDa
GenBank蛋白编号BC014181
基因名称 COQ6
Gene ID (NCBI) 51004
RRIDAB_10644143
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y2Z9
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

COQ6(Coenzyme Q10 monooxygenase 6) is also named CGI-10 and belongs to the ubiH/COQ6 family. It is an evolutionarily conserved flavin-dependent monooxygenase required for the biosynthesis of coenzyme Q10 or ubiquinone. It has 3 isoforms with a molecular mass of 51 kDa, 43 kDa and 49 kDa. In the inner ear, Coq6 is expressed in the spiral ganglion, stria vascularis cells, and spiral ligament(PMID:21540551 ). Defects in COQ6 are the cause of coenzyme Q10 deficiency, primary, type 6 (COQ10D6).