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验证数据展示

  • IHC staining of mouse lung using 22302-1-AP (same clone as 22302-1-PBS)

    IHC staining of mouse lung using 22302-1-AP (same clone as 22302-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 22302-1-AP (COL6A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22302-1-PBS in a different storage buffer formulation.

  • WB analysis using 22302-1-AP (same clone as 22302-1-PBS)

    WB analysis using 22302-1-AP (same clone as 22302-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22302-1-AP (COL6A6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22302-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 22302-1-AP (same clone as 22302-1-PBS)

    IHC staining of mouse heart using 22302-1-AP (same clone as 22302-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 22302-1-AP (COL6A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22302-1-PBS in a different storage buffer formulation.

COL6A6 Polyclonal antibody, PBS Only

COL6A6 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 22302-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

22302-1-PBS targets COL6A6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 collagen type VI alpha 6
别名
计算分子量 247 kDa
观测分子量167 kDa, 250 kDa
GenBank蛋白编号NM_001102608
基因名称 COL6A6
Gene ID (NCBI) 131873
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDA6NMZ7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Collagen type VI alpha 6 chain (COL6A6) belongs to the collagen VI (COL6) family which acts as a vital role in the extracellular matrix. COL6A6 encodes a 2,262-amino acid protein that contains multiple von Willebrand factor domains and forms a component of the basal lamina of epithelial cells (PMID: 33747955). COL6A6 is a novel tumor suppressor gene in NSCLC and can serve as a potentially valuable prognostic biomarker and therapeutic target for NSCLC (PMID: 35116307).

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