验证数据展示
产品信息
CL488-66343 targets CLIC4 in applications and shows reactivity with human, pig, rat samples.
| 经测试应用 | Application Description |
| 经测试反应性 | human, pig, rat |
| 免疫原 | CLIC4 fusion protein Ag2942 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | chloride intracellular channel 4 |
| 别名 | CLIC4, CLIC4L, DKFZp566G223, FLJ38640, H1, huH1, MTCLIC, p64H1 |
| 计算分子量 | 253 aa, 29 kDa |
| 观测分子量 | 29 kDa |
| GenBank蛋白编号 | BC012444 |
| 基因名称 | CLIC4 |
| Gene ID (NCBI) | 25932 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q9Y696 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIC4 is a p53- and tumor necrosis factor alpha-regulated cytoplasmic and mitochondrial protein that belongs to the CLIC family of intracellular chloride channels. CLICs have actions distinct from traditional cell membrane chloride channels, including formation of ion channels in intracellular organelles and roles in membrane trafficking, apoptosis, and cell differentiation.