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验证数据展示

  • WB analysis of Jurkat using 17192-1-AP (same clone as 17192-1-PBS)

    WB analysis of Jurkat using 17192-1-AP (same clone as 17192-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 17192-1-AP (CFP Antibody) at dilution of 1:300 incubated at 4 degree celsius over night. This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

  • IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

    IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

Properdin/PFC Polyclonal antibody, PBS Only

Properdin/PFC Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 17192-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

CFP, PFC, complement factor properdin, Complement factor P, BFD

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

17192-1-PBS targets Properdin/PFC in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Properdin/PFC fusion protein Ag9798 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 complement factor properdin
别名 CFP, PFC, complement factor properdin, Complement factor P, BFD
计算分子量 469 aa, 51 kDa
观测分子量 50 kDa
GenBank蛋白编号BC015756
基因名称 CFP
Gene ID (NCBI) 5199
RRIDAB_2878359
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP27918
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).