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CEP-33779

CAS号

1257704-57-6

分子式

C24H26N6O2S

主要靶点

JAK

仅限科研使用

Cat No : CM04887

Print datasheet

Synonyms

Inhibitor|Janus kinase|JAK2|JAK|inhibit|CEP 33779|CEP33779|CEP-33779

验证数据展示

  • CAS No.: 1257704-57-6

    CEP-33779
    CAS#: 1257704-57-6

产品信息

CAS号 1257704-57-6
分子式 C24H26N6O2S
主要靶点 JAK
主要通路 表观遗传|蛋白酪氨酸激酶|干细胞|血管生成|JAK/STAT 信号通路
分子量 462.57
纯度 99.41%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Inhibitor|Janus kinase|JAK2|JAK|inhibit|CEP 33779|CEP33779|CEP-33779

靶点活性

JAK2:1.8±0.6 nM

溶解度

DMSO:16.67 mg/mL (36.03 mM)

参考文献

1.Stump KL, et al. Arthritis Res Ther, 2011, 13(2), R68.
2.Lu LD, et al. J Immunol, 2011, 187(7), 3840-3853.
3.Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond–Blackfan anemia[J]. Cell Death & Disease. 2020, 11(2): 1-11.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2