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验证数据展示

  • WB analysis using 10421-1-AP (same clone as 10421-1-PBS)

    WB analysis using 10421-1-AP (same clone as 10421-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10421-1-AP (CEA antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10421-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 10421-1-AP (same clone as 10421-1-PBS)

    IHC staining of human colon cancer using 10421-1-AP (same clone as 10421-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10421-1-AP (CEA antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10421-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CEA/CD66e antibody included
  • IHC staining of human colon cancer using 10421-1-AP (same clone as 10421-1-PBS)

    IHC staining of human colon cancer using 10421-1-AP (same clone as 10421-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10421-1-AP (CEA antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10421-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CEA/CD66e antibody included
  • IF Staining of human colon cancer using 10421-1-AP (same clone as 10421-1-PBS)

    IF Staining of human colon cancer using 10421-1-AP (same clone as 10421-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human colon cancer tissue using CEA antibody (10421-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 10421-1-PBS in a different storage buffer formulation.

  • IF Staining of human colon cancer using 10421-1-AP (same clone as 10421-1-PBS)

    IF Staining of human colon cancer using 10421-1-AP (same clone as 10421-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human colon cancer tissue using CEA antibody (10421-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 10421-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

CEA/CD66e Polyclonal antibody, PBS Only

CEA/CD66e Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 10421-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF-P, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CEA/CD66e Ready-To-Use IHC Kit. CEA/CD66e primary antibody included.

产品信息

10421-1-PBS targets CEA/CD66e in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag0672

Product name: Recombinant human CEACAM5 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-300 aa of BC034671

Sequence: MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 carcinoembryonic antigen-related cell adhesion molecule 5
别名
计算分子量 77 kDa
观测分子量180-200 kDa, 77 kDa
GenBank蛋白编号BC034671
基因名称 CEA
Gene ID (NCBI) 1048
RRIDAB_2244691
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP06731
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e, is a cell surface glycoprotein belonging to the immunoglobulin superfamily, mainly serving as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEA inhibits anoikis and plays a role in tumorigenesis and metastasis. CEA has been found to be overexpressed in a wide variety of human cancers, including colon, breast, and lung (PMID: 17167768). CEA is a tumor marker and is routinely exploited for diagnosis.

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