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CDN1163

CAS号

892711-75-0

分子式

C20H20N2O2

主要靶点

Calcium Channel

仅限科研使用

Cat No : CM03061

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Synonyms

inhibit|Inhibitor|Calcium Channel|CalciumChannel|Ca2+ channels|Ca channels|CDN 1163|CDN1163|CDN-1163

验证数据展示

  • CAS No.: 892711-75-0

    CDN1163
    CAS#: 892711-75-0

产品信息

CAS号 892711-75-0
分子式 C20H20N2O2
主要靶点 Calcium Channel
主要通路 代谢|离子通道
分子量 320.39
纯度 ≥95%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 inhibit|Inhibitor|Calcium Channel|CalciumChannel|Ca2+ channels|Ca channels|CDN 1163|CDN1163|CDN-1163

体内活性

CDN1163, which markedly lowered fasting blood glucose, improved glucose tolerance, and ameliorated hepatosteatosis but did not alter glucose levels or body weight in lean controls.?Importantly, CDN1163-treated ob/ob mice maintained euglycemia comparable with that of lean mice for >6 weeks after cessation of CDN1163 administration[1].

溶解度

DMSO:50 mg/mL (156.06 mM)

参考文献

1.Kang S , Dahl R , Hsieh W , et al. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders[J]. Journal of Biological Chemistry, 2015:jbc.M115.705012.
2.Rizwan, Qaisar, Shylesh, et al. Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness.[J]. Redox biology, 2018.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2