验证数据展示
Planning an IHC experiment? We recommend our IHCeasy CDKN1C Ready-To-Use IHC Kit. CDKN1C primary antibody included.
产品信息
19804-1-AP targets p57KIP2-Specific in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| 别名 | BWCR, BWS, CDKN1C, KIP2, p57, p57Kip2, WBS |
| 计算分子量 | 32 kDa |
| GenBank蛋白编号 | NM_000076 |
| 基因名称 | p57 Kip2/CDKN1C |
| Gene ID (NCBI) | 1028 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P49918 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life. The antibody is specific to CDKN1C.
