验证数据展示
产品信息
CL488-65123 targets CD62L (L-Selectin) in applications and shows reactivity with Mouse samples.
| 经测试应用 | Application Description |
| 经测试反应性 | Mouse |
| 免疫原 | C3H/eb mouse B lymphoma 38C-13 种属同源性预测 |
| 宿主/亚型 | Rat / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | selectin, lymphocyte |
| 别名 | AI528707, CD62L, L selectin, LECAM 1, Lnhr, Ly 22, Ly m22, Lyam 1, Lyam1, selectin, lymphocyte, Sell |
| GenBank蛋白编号 | BC052681 |
| 基因名称 | CD62L |
| Gene ID (NCBI) | 20343 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 488 nm / 515 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P18337 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3 |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
L-selectin, also known as SELL or CD62L, is a member of the selectin family of adhesion molecules that includes E-selectin and P-selectin (PMID: 2663882, 2473156, 1382078). L-selectin is a protein with the calculated molecular mass of 42 kDa but actually 95-105 kDa on neutrophils and 74 kDa on lymphocytes because of the highly glycosylation (PMID: 1694883, 1695155). L-selectin is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). L-selectin mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and are also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078).