验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 17336-1-AP
产品信息
CL488-17336 targets CD1d in applications and shows reactivity with human, mouse samples.
| 经测试应用 | Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 | CD1d fusion protein Ag11371 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | CD1d molecule |
| 别名 | CD1A, CD1D, CD1d molecule, R3, R3G1 |
| 计算分子量 | 335 aa, 38 kDa |
| GenBank蛋白编号 | BC027926 |
| 基因名称 | CD1D |
| Gene ID (NCBI) | 912 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P15813 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CD1d is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. CD1d is an antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on NKT cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines. The molecular weight of unglycosylated CD1d is 38 kDa, while glycosylated form of CD1d is 48-50 kDa.