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验证数据展示

  • WB analysis using 68334-1-Ig (same clone as 68334-1-PBS)

    WB analysis using 68334-1-Ig (same clone as 68334-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68334-1-Ig (CC2D1A antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68334-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse testis using 68334-1-Ig (same clone as 68334-1-PBS)

    IHC staining of mouse testis using 68334-1-Ig (same clone as 68334-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 68334-1-Ig (CC2D1A antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68334-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CC2D1A antibody included
  • IF Staining of HeLa using 68334-1-Ig (same clone as 68334-1-PBS)

    IF Staining of HeLa using 68334-1-Ig (same clone as 68334-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using CC2D1A antibody (68334-1-Ig, Clone: 1C11G2 ) at dilution of 1:1000 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68334-1-PBS in a different storage buffer formulation.

CC2D1A Monoclonal antibody, PBS Only

CC2D1A Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 68334-1-PBS

产品说明书

CloneNo. 1C11G2

宿主/亚型

Mouse / IgG1

种属反应性

Human, Mouse, Rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

CC2D1A, FLJ20241, FLJ41160, FREUD 1, Freud 1/Aki1, MRT3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CC2D1A Ready-To-Use IHC Kit. CC2D1A primary antibody included.

产品信息

68334-1-PBS targets CC2D1A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 Human, Mouse, Rat
免疫原 CC2D1A fusion protein Ag10363 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 coiled-coil and C2 domain containing 1A
别名 CC2D1A, FLJ20241, FLJ41160, FREUD 1, Freud 1/Aki1, MRT3
计算分子量 951 aa, 104 kDa
观测分子量 130 kDa
GenBank蛋白编号BC064981
基因名称 CC2D1A
Gene ID (NCBI) 54862
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ6P1N0
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CC2D1A (coiled-coil and C2 domain-containing 1A), also known as Freud-1, Aki1 or TAPE (TBK1-associated protein in endolysosomes), is a evolutionary conserved protein located in different subcellular compartments, including the nucleus, centrosome, and endolysosomes. It acts as a scaffold protein that interacts with various proteins and plays diverse biological roles. Mutations in CC2D1A have been linked to nonsyndromic mental retardation (NMSR) and generate a truncated 85-kDa product. Several isoforms of CC2D1A proteins have also been described: 120 /130-kDa doublet of long isoform and 67 kDa short isoform. The short isoform of CC2D1A has been identified as the predominant isoform in rodent cells, while the long isoform is more abundant in human cells. Recently it has been reported that CC2D1A/TAPE is the first innate immune regulator implicated in both TLR and RLR signaling at a very early step.