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CBP/EP300-IN-1

CBP/EP300-IN-1是一种 CBP/EP300 溴结构域抑制剂。

CAS号

2443789-32-8

分子式

C23H23FN2O5

主要靶点

Epigenetic Reader Domain

仅限科研使用

Cat No : CM03983

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Synonyms

验证数据展示

  • CAS No.: 2443789-32-8

    CBP/EP300-IN-1
    CAS#: 2443789-32-8

产品信息

CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.

CAS号 2443789-32-8
分子式 C23H23FN2O5
主要靶点 Epigenetic Reader Domain
主要通路 表观遗传
分子量 426.44
纯度 98.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

溶解度

DMSO:62.5 mg/mL (146.56 mM)

参考文献

1.Conery A R , Centore R C , Neiss A , et al. Correction: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma.[J]. eLife,5,(2016-01-04), 2016, 5.
2.Xiang Q , Wang C , Zhang Y , et al. Discovery and optimization of 1-(1 H -indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer[J]. European Journal of Medicinal Chemistry, 2018:S0223523418301090.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2