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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of mouse liver using 14335-1-AP (same clone as 14335-1-PBS)

    WB analysis of mouse liver using 14335-1-AP (same clone as 14335-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 14335-1-AP (CADM1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14335-1-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 14335-1-AP (same clone as 14335-1-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 14335-1-AP (same clone as 14335-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 14335-1-AP (CADM1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14335-1-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 14335-1-AP (same clone as 14335-1-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 14335-1-AP (same clone as 14335-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 14335-1-AP (CADM1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14335-1-PBS in a different storage buffer formulation.

CADM1 Polyclonal antibody, PBS Only

CADM1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 14335-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

NECL-2, NECL2, Necl 2, IGSF4A, IgSF4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

14335-1-PBS targets CADM1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 CADM1 fusion protein Ag5621 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cell adhesion molecule 1
别名 NECL-2, NECL2, Necl 2, IGSF4A, IgSF4
计算分子量 49 kDa
观测分子量 49-60 kDa
GenBank蛋白编号BC047021
基因名称 CADM1
Gene ID (NCBI) 23705
RRIDAB_2243801
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BY67
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CADM1 (cell adhesion molecule 1), also referred to as SgIGSF, Necl-2 or TSLC-1, is a cell adhesion molecule belonging to the immunoglobulin superfamily. It can mediate homophilic and heterophilic cell-cell adhesion. CADM1 is expressed by a variety of cells including neurons, mast cells, spermatogonia, pancreatic islet cells, epithelial cells such as lung alveolar cells and biliary epithelial cells. CADM1 is involved in carcinoma pathogenesis and the expression of CADM1 is frequently down-regulated in various tumors derived from epithelial cells. It acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. (PMID: 18332875; 17326163; 20340131)