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验证数据展示

  • WB analysis of SH-SY5Y using 22145-1-AP (same clone as 22145-1-PBS)

    WB analysis of SH-SY5Y using 22145-1-AP (same clone as 22145-1-PBS)

    WB result of CACNA2D2 antibody (22145-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CACNA2D2 transfected SH-SY5Y cells. This data was developed using the same antibody clone with 22145-1-PBS in a different storage buffer formulation.

  • WB analysis using 22145-1-AP (same clone as 22145-1-PBS)

    WB analysis using 22145-1-AP (same clone as 22145-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22145-1-AP (CACNA2D2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22145-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

CACNA2D2 Polyclonal antibody, PBS Only

CACNA2D2 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 22145-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

22145-1-PBS targets CACNA2D2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 CACNA2D2 fusion protein Ag17580 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 calcium channel, voltage-dependent, alpha 2/delta subunit 2
别名
计算分子量 1145 aa, 129 kDa
观测分子量100-112 kDa
GenBank蛋白编号BC152438
基因名称 CACNA2D2
Gene ID (NCBI) 9254
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NY47
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2), also known as CASVDD. It is expected to be located in cell membrane. The protein is predominantly present in cerebellar cortex. Present in various lung tumor cell lines, while it is absent in normal lung (at protein level). Highly expressed in heart, lung, testis, pancreas and skeletal muscle. Also expressed in kidney, liver, placenta and brain (PMID: 10766861). The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel (PMID: 15111129). The molecular weight of CACNA2D2 is 129 kDa, and it can recognize other isoforms, which can be cut into fragments.