Bimatoprost acid

CAS号

38344-08-0

分子式

C23H32O5

主要靶点

GPR

仅限科研使用

Cat No : CM10319

Print datasheet

Synonyms

17-phenyl trinor PGF2α|17-phenyl trinor Prostaglandin F2a|17-phenyl trinor PGF2alpha|17-phenyl trinor PGF2a|17-phenyl trinor Prostaglandin F2alpha|17-phenyl trinor Prostaglandin F2α|Bimatoprost acid|prostanoid selective FP receptor



产品信息

CAS号 38344-08-0
分子式 C23H32O5
主要靶点 GPR
主要通路 G 蛋白偶联受体|内分泌与激素
分子量 388.5
纯度 99.29%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 17-phenyl trinor PGF2α|17-phenyl trinor Prostaglandin F2a|17-phenyl trinor PGF2alpha|17-phenyl trinor PGF2a|17-phenyl trinor Prostaglandin F2alpha|17-phenyl trinor Prostaglandin F2α|Bimatoprost acid|prostanoid selective FP receptor

溶解度

DMSO:65 mg/mL (167.31 mM)

参考文献

1.1.Yulia K ,  Kinuthia M W ,  Thoa T , et al. New Human Organotypic Corneal Tissue Model for Ophthalmic Drug Delivery Studies[J]. Investigative Ophthalmology & Visual Science, 2018, 59(7):2880-2898.
2.Klimko PG, Sharif NA. Discovery, characterization and clinical utility of prostaglandin agonists for the treatment of glaucoma. Br J Pharmacol. 2018 Apr 17. doi: 10.1111/bph.14327. [Epub ahead of print] Review. PubMed PMID: 29665040.
3.Shen J, Goodkin ML, Tong W, Attar M. Ocular pharmacokinetics and tolerability of bimatoprost ophthalmic solutions administered once or twice daily in rabbits, and clinical dosing implications. Clin Ophthalmol. 2017 Sep 28;11:1761-1767. doi: 10.2147/OPTH.S143428. eCollection 2017. Erratum in: Clin Ophthalmol. 2018 Aug 17;12:147PubMed PMID: 29026287; PubMed Central PMCID: PMC5627754.
4.Krupa M, Chodyński M, Ostaszewska A, Cmoch P, Dams I. A Novel Convergent Synthesis of the Potent Antiglaucoma Agent Tafluprost. Molecules. 2017 Jan 31;22(2). pii: E217. doi: 10.3390/molecules22020217. PubMed PMID: 28146132.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2