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Benzydamine hydrochloride

Benzydamine hydrochloride (AF864) 是一种局部作用的非甾体抗炎药，具有局部麻醉和镇痛作用。它也是前列腺素合成酶抑制剂，有抗细菌活性。

CAS号

132-69-4

分子式

C19H23N3O·HCl

主要靶点

COX|Antibacterial|PGE Synthase

仅限科研使用

Cat No : CM05467

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Synonyms

盐酸苄达明|Benzydamine HCl|AF864

验证数据展示

  • CAS No.: 132-69-4

    Benzydamine hydrochloride
    CAS#: 132-69-4

产品信息

Benzydamine hydrochloride, a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.

CAS号 132-69-4
分子式 C19H23N3O·HCl
主要靶点 COX|Antibacterial|PGE Synthase
主要通路 免疫与炎症|神经科学|微生物学
分子量 345.87
纯度 98.42%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 盐酸苄达明|Benzydamine HCl|AF864

体内活性

Benzydamine significantly lower the incidence of postoperative sore throat (POST). At 6 hours after extubation, the incidence of POST is 17.0%. Spraying benzydamine hydrochloride on the ETT cuff is a simple and effective method to reduce the incidence and severity of POST. [2]

溶解度

DMSO:64 mg/mL (185 mM),H2O:63 mg/mL (182.1 mM),Ethanol:64 mg/mL (185 mM)

参考文献

1.Epstein JB, et al. Int J Radiat Oncol Biol Phys, 1989, 16(6), 1571-1575.
2.Hung NK, et al. Anesth Analg, 2010, 111(4), 882-886.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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=
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C1   V1   C2   V2