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Benzoic acid

CAS号

65-85-0

分子式

C7H6O2

主要靶点

Endogenous Metabolite|Others|Antibacterial|Antifungal

仅限科研使用

Cat No : CM00097

Print datasheet

Synonyms

Bacterial|Benzoic acid|Fungal|FEMA 2131|FEMA2131|FEMA-2131|EndogenousMetabolite|Dracylic acid|Endogenous Metabolite|苯甲酸|Inhibitor|inhibit

验证数据展示

  • CAS No.: 65-85-0

    Benzoic acid
    CAS#: 65-85-0

产品信息

CAS号 65-85-0
分子式 C7H6O2
主要靶点 Endogenous Metabolite|Others|Antibacterial|Antifungal
主要通路 微生物学|代谢|微生物学
分子量 122.12
纯度 99.41%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Bacterial|Benzoic acid|Fungal|FEMA 2131|FEMA2131|FEMA-2131|EndogenousMetabolite|Dracylic acid|Endogenous Metabolite|苯甲酸|Inhibitor|inhibit

体内活性

Benzoic acid在酸性生长情况下,容易进入细胞经过细胞内离子化大幅降低细胞内pH值和三磷酸腺苷酶水平。Benzoic acid会被受激中性粒细胞产生的羟基自由基氧化。Benzoic acid通过人体皮肤的平均吸收与对大鼠的研究没有差异,吸收受皮肤厚度的影响很小。Benzoic acid通过人体皮肤细胞膜转运的最大速率为每小时16.54 μg/cm2,在24小时后受体液体中的实际剂量为70.6％。

溶解度

DMSO:60 mg/mL (491.32 mM);Ethanol:24 mg/mL (196.52 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

参考文献

1.Tsuji A, et al. Pharm Res, 1994, 11(1), 30-37.
2.Tremblay GC, et al. Pharmacol Ther, 1993, 60(1), 63-90.
3.Elder DJ, et al. FEMS Microbiol Rev, 1994, 13(4), 441-468.
4.van de Sandt JJ, et al. Regul Toxicol Pharmacol, 2004, 39(3), 271-281.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2