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Bendazac

CAS号

20187-55-7

分子式

C16H14N2O3

主要靶点

Others

仅限科研使用

Cat No : CM01640

Print datasheet

Synonyms

Bendazolic acid|Bendazac|cataractogenic|choleretic|antinecrotic|antilipidaemic|AF 983|AF983|AF-983|denaturation|inflammatory|inhibit|Inhibitor|protein

验证数据展示

  • CAS No.: 20187-55-7

    Bendazac
    CAS#: 20187-55-7

产品信息

CAS号 20187-55-7
分子式 C16H14N2O3
主要靶点 Others
主要通路 其他
分子量 282.29
纯度 98.13%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Bendazolic acid|Bendazac|cataractogenic|choleretic|antinecrotic|antilipidaemic|AF 983|AF983|AF-983|denaturation|inflammatory|inhibit|Inhibitor|protein

体外活性

Bendazac（bendazac L-lysine和sodium）可抑制蛋白质糖化的早期阶段及荧光高级糖化终产品的形成。Bendazac lysine（20 mM）在抑制荧光发展方面证明比相应的sodium salt更有效（67%抑制vs 35%抑制）。对于furosine水平，未发现显著差异；无论是bendazac lysine还是sodium salt，约40%的抑制作用被产生。Bendazac明显可以抑制人类晶状体crystallins的糖化，这可以通过跟踪晶状体蛋白荧光的特定变化有效监测[1]。

溶解度

DMSO:60 mg/mL (212.55 mM)

参考文献

1.Marques C , Ramalho J S , Pereira P , et al. Bendazac decreases in vitro glycation of human lens crystallins. Decrease of in vitro protein glycation by bendazac[J]. Documenta Ophthalmologica, 1995, 90(4):395-404.
2.Lewis B S , Rixon K C , Harding J J . Bendazac prevents cyanate binding to soluble lens proteins and cyanate-induced phase-separation opacities in vitro: a possible mechanism by which bendazac could delay cataract[J]. Experimental Eye Research, 1986, 43(6):0-979.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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