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BTB-1

BTB-1 (NSC156750) 是一种新型的有丝分裂运动蛋白 Kif18A 的小分子抑制剂，IC50值为1.69 μM。

CAS号

86030-08-2

分子式

C12H8ClNO4S

主要靶点

Microtubule Associated

仅限科研使用

Cat No : CM05116

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Synonyms

NSC156750|BTB 1

验证数据展示

  • CAS No.: 86030-08-2

    BTB-1
    CAS#: 86030-08-2

产品信息

BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.

CAS号 86030-08-2
分子式 C12H8ClNO4S
主要靶点 Microtubule Associated
主要通路 细胞骨架
分子量 297.71
纯度 99.71%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 NSC156750|BTB 1

靶点活性

Kif18A:1.69 μM.

溶解度

Ethanol:20 mM,DMSO:100 mM

参考文献

1.Catarinella M., et al. BTB-1: a small molecule inhibitor of the mitotic motor protein Kif18A. Angew Chem Int Ed Engl. 2009;48(48):9072-6.
2.Braun J., et al. Synthesis and biological evaluation of optimized inhibitors of the mitotic kinesin Kif18A. ACS Chem Biol. 2015 Feb 20;10(2):554-60.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2