BTB-1

CAS号

86030-08-2

分子式

C12H8ClNO4S

主要靶点

Microtubule Associated

仅限科研使用

Cat No : CM05116

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Synonyms

Inhibitor|mitotic kinesin Kif18A|MicrotubuleAssociated|Microtubule Associated|Microtubule/Tubulin|NSC 156750|NSC156750|NSC-156750|inhibit|BTB 1|BTB1|BTB-1



产品信息

CAS号 86030-08-2
分子式 C12H8ClNO4S
主要靶点 Microtubule Associated
主要通路 细胞骨架
分子量 297.71
纯度 99.71%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Inhibitor|mitotic kinesin Kif18A|MicrotubuleAssociated|Microtubule Associated|Microtubule/Tubulin|NSC 156750|NSC156750|NSC-156750|inhibit|BTB 1|BTB1|BTB-1

靶点活性

KIF18A:1.69 μM.

溶解度

Ethanol:20 mM;DMSO:45 mg/mL (151.15 mM)

参考文献

1.Catarinella M., et al. BTB-1: a small molecule inhibitor of the mitotic motor protein Kif18A. Angew Chem Int Ed Engl. 2009;48(48):9072-6.
2.Braun J., et al. Synthesis and biological evaluation of optimized inhibitors of the mitotic kinesin Kif18A. ACS Chem Biol. 2015 Feb 20;10(2):554-60.

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