BSAP,PAX5 Polyclonal antibody
BSAP,PAX5 Polyclonal Antibody for FC, WB,ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
FC, WB,ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
The immunogen of 21388-1-AP is BSAP,PAX5 Fusion Protein expressed in E. coli.
| Tested Applications | FC, WB,ELISA |
| Tested Reactivity | human |
| Immunogen | BSAP,PAX5 fusion protein Ag16023 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | paired box 5 |
| Synonyms | BSAP, paired box 5, Paired box protein Pax 5, PAX5 |
| Calculated Molecular Weight | 391 aa, 42 kDa |
| GenBank Accession Number | BC156927 |
| Gene Symbol | PAX5 |
| Gene ID (NCBI) | 5079 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q02548 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PAX5, also named B-cell specific activator protein (BSAP), is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL, PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.