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BRM/BRG1 ATP Inhibitor-1

CAS号

2270879-17-7

分子式

C11H9F3N4O2S

主要靶点

Epigenetic Reader Domain

仅限科研使用

Cat No : CM11423

Print datasheet

Synonyms

dual inhibitor|EpigeneticReaderDomain|Epigenetic Reader Domain|ATPase inhibitor|BRM, BRG1|BRM/BRG1|BRM/BRG1 ATP Inhibitor 1|BRM/BRG1 ATP Inhibitor1|BRM/BRG-1 ATP Inhibitor-1|BRM/BRG1 ATP Inhibitor-1|anticancer|(BRG1)/SMARCA4|(BRM)/SMARCA2|Inhibitor|inhibit

验证数据展示

  • CAS No.: 2270879-17-7

    BRM/BRG1 ATP Inhibitor-1
    CAS#: 2270879-17-7

产品信息

CAS号 2270879-17-7
分子式 C11H9F3N4O2S
主要靶点 Epigenetic Reader Domain
主要通路 表观遗传
分子量 318.27
纯度 99.84%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 dual inhibitor|EpigeneticReaderDomain|Epigenetic Reader Domain|ATPase inhibitor|BRM, BRG1|BRM/BRG1|BRM/BRG1 ATP Inhibitor 1|BRM/BRG1 ATP Inhibitor1|BRM/BRG-1 ATP Inhibitor-1|BRM/BRG1 ATP Inhibitor-1|anticancer|(BRG1)/SMARCA4|(BRM)/SMARCA2|Inhibitor|inhibit

靶点活性

BRM/BRG1:﹤0.005 μM

溶解度

DMSO:250 mg/mL (785.50 mM)

参考文献

1.Papillon JPN, et al. Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. J Med Chem. 2018 Nov 21;61(22):10155-10172

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2