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BML-278

CAS号

120533-76-8

分子式

C24H25NO4

主要靶点

Histone Methyltransferase|Sirtuin

仅限科研使用

Cat No : CM08678

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Synonyms

BML278|BML-278|BML 278|HistoneMethyltransferase|Histone Methyltransferase|SIRT1

验证数据展示

  • CAS No.: 120533-76-8

    BML-278
    CAS#: 120533-76-8

产品信息

CAS号 120533-76-8
分子式 C24H25NO4
主要靶点 Histone Methyltransferase|Sirtuin
主要通路 表观遗传|DNA 损伤和修复|表观遗传
分子量 391.46
纯度 100%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Shipping with blue ice.
别名 BML278|BML-278|BML 278|HistoneMethyltransferase|Histone Methyltransferase|SIRT1

靶点活性

SIRT1:1 μM(EC50)

溶解度

DMSO:5.63 mg/mL (14.37 mM)

参考文献

1.Adamkova K, et al. SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development. J Anim Sci Biotechnol. 2017 Nov 1;8:83.
2.Mai A, et al. Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors. J Med Chem. 2009 Sep 10;52(17):5496-504.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2