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BI-3812

CAS号

2166387-64-8

分子式

C26H32ClN7O5

主要靶点

BCL

仅限科研使用

Cat No : CM11459

Print datasheet

Synonyms

BCL6 BTB|Bcl-6|Bcl-2 Family|BI 3812|BI3812|BI-3812|Inhibitor|inhibit

验证数据展示

  • CAS No.: 2166387-64-8

    BI-3812
    CAS#: 2166387-64-8

产品信息

CAS号 2166387-64-8
分子式 C26H32ClN7O5
主要靶点 BCL
主要通路 凋亡
分子量 558.03
纯度 99.79%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 BCL6 BTB|Bcl-6|Bcl-2 Family|BI 3812|BI3812|BI-3812|Inhibitor|inhibit

靶点活性

BCL6 BTB:≤3 nM (IC50)

体内活性

BI-3812是一种BCL6抑制剂，其半抑制浓度(IC50) ≤3 nM。对于细胞内BCL6，BI-3812展现出40 nM的IC50[1]。

溶解度

DMSO:19.83 mg/mL (35.54 mM)

参考文献

1.Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20(12):2860-2875.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2