BCL6 Monoclonal antibody
BCL6 Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
3B9D11
验证数据展示
产品信息
60184-1-Ig targets BCL6 in ELISA applications and shows reactivity with human samples.
| Tested Applications | ELISA |
| Tested Reactivity | human |
| Immunogen | BCL6 fusion protein Ag15519 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | B-cell CLL/lymphoma 6 |
| Synonyms | B cell CLL/lymphoma 6, ZBTB27, Zinc finger protein 51, ZNF51 |
| Calculated Molecular Weight | 706 aa, 79 kDa |
| GenBank Accession Number | BC150184 |
| Gene Symbol | BCL6 |
| Gene ID (NCBI) | 604 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P41182 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
BCl6, a zinc finger transcription factor, contains a N-terminal BTB/POZ domain and C-terminal zinc finger DNA-binding motifs and represses transcription of a wide range of target proteins and microRNAs. BCL6 protein has been reported as a master regulator of B lymphocyte development and growth, and altered BCL6 protein expression was implicated in pathogenesis of diverse human hematologic malignancies, especially in the diffuse large B cell lymphoma (DLBCL). BCL6 is required for the development of T follicular helper T cells (TFH), a helper T cell subset required for the formation of mature and productive GCs. BCL6 has also been shown to play important regulatory roles in macrophages.