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Azide-PEG12-Tos

CAS号

1821464-56-5

分子式

C31H55N3O14S

主要靶点

PROTAC Linker|Others

仅限科研使用

Cat No : CM10884

Print datasheet

Synonyms

Azide PEG12 Tos|AzidePEG12Tos|Azide-PEG-12-Tos|Azide-PEG12-Tos|Inhibitor|inhibit|PROTAC Linker|PROTAC Linkers|PROTACLinker|PEGs|叠氮-十二聚乙二醇-对甲苯磺酰酯

验证数据展示

  • CAS No.: 1821464-56-5

    Azide-PEG12-Tos
    CAS#: 1821464-56-5

产品信息

CAS号 1821464-56-5
分子式 C31H55N3O14S
主要靶点 PROTAC Linker|Others
主要通路 PROTAC
分子量 725.85
纯度 98.72%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Azide PEG12 Tos|AzidePEG12Tos|Azide-PEG-12-Tos|Azide-PEG12-Tos|Inhibitor|inhibit|PROTAC Linker|PROTAC Linkers|PROTACLinker|PEGs|叠氮-十二聚乙二醇-对甲苯磺酰酯

体外活性

PROTACs通过连接器连接两种不同的配体；其中一个是E3泛素连接酶的配体，另一个则是目标蛋白的配体。PROTACs利用细胞内的泛素-蛋白酶体系统，有选择性地降解目标蛋白[1]。

参考文献

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2