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Apararenone

Apararenone (MT-3995) 是一种新型的、非甾体类盐皮质激素受体 (mineralocorticoid receptor) 拮抗剂，正在开发用于糖尿病性肾病和非酒精性脂肪性肝炎的研究。

CAS号

945966-46-1

分子式

C17H17FN2O4S

主要靶点

Glucocorticoid Receptor

仅限科研使用

Cat No : CM05143

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Synonyms

MT-3995

验证数据展示

  • CAS No.: 945966-46-1

    Apararenone
    CAS#: 945966-46-1

产品信息

Apararenone is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy.

CAS号 945966-46-1
分子式 C17H17FN2O4S
主要靶点 Glucocorticoid Receptor
主要通路 内分泌与激素
分子量 364.39
纯度 99.65%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 MT-3995

体内活性

A phase II clinical trial has been initiated among patients with non-alcoholic steatohepatitis (NASH) in Japan[1].

溶解度

DMSO:125 mg/mL (343.04 mM)

参考文献

1.Kolkhof P, et al. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor antagonists: 60 years of research and development. J Endocrinol. 2017 Jul;234(1):T125-T140.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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