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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 22425-1-AP (same clone as 22425-1-PBS)

    WB analysis using 22425-1-AP (same clone as 22425-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22425-1-AP (Adiponectin receptor 1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22425-1-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 22425-1-AP (same clone as 22425-1-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 22425-1-AP (same clone as 22425-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 22425-1-AP (Adiponectin receptor 1 antibody) at dilution of 1:100 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22425-1-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 22425-1-AP (same clone as 22425-1-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 22425-1-AP (same clone as 22425-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 22425-1-AP (Adiponectin receptor 1 antibody) at dilution of 1:100 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22425-1-PBS in a different storage buffer formulation.

Adiponectin receptor 1 Polyclonal antibody, PBS Only

Adiponectin receptor 1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 22425-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

ADIPOR1, Adiponectin receptor protein 1, PAQR1, CGI-45, CGI45

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

22425-1-PBS targets Adiponectin receptor 1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Adiponectin receptor 1 fusion protein Ag18187 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 adiponectin receptor 1
别名 ADIPOR1, Adiponectin receptor protein 1, PAQR1, CGI-45, CGI45
计算分子量 375 aa, 43 kDa
观测分子量45 kDa
GenBank蛋白编号BC010743
基因名称 Adiponectin receptor 1
Gene ID (NCBI) 51094
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96A54
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin have been identified: adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). They are seven-transmembrane domain receptors and mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is found in many tissues, being particularly abundant in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver (PMID: 24417942). AdipoR1 has a high affinity for globular adiponectin and a very low affinity for full-length adiponectin. AdipoR2 has an intermediate affinity for both forms.