Acacetin

Acacetin (5,7-Dihydroxy-4'-methoxyflavone) 是一种来自狗舌草的口服有效类黄酮。它停在 PI3Kγ 的 ATP 结合口袋中,可导致癌细胞周期停滞,并诱导细胞凋亡和自噬。它有抗癌和抗炎活性,有潜力研究疼痛相关疾病。

CAS号

480-44-4

分子式

C16H12O5

主要靶点

COX|Autophagy|Apoptosis|IAP

仅限科研使用

Cat No : CM00613

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Synonyms

金合欢素|4'-Methoxyapigenin|5,7-Dihydroxy-4'-methoxyflavone|Linarigenin



产品信息

Acacetin is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant activity in various research models.

CAS号 480-44-4
分子式 C16H12O5
主要靶点 COX|Autophagy|Apoptosis|IAP
主要通路 凋亡|免疫与炎症|神经科学|自噬
分子量 284.3
纯度 98.00%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 金合欢素|4'-Methoxyapigenin|5,7-Dihydroxy-4'-methoxyflavone|Linarigenin

溶解度

DMSO:>10.7 mg/mL

参考文献

1.Zielińska, S. and Matkowski, A. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochem. Rev. 13(2), 391-416 (2014).
2.Jaganathan, S.K. and Mandal, M. Antiproliferative effects of honey and of its polyphenols: A review. J. Biomed. Biotechnol. 2009, 830616 (2009).

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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