ATM Polyclonal antibody

ATM Polyclonal Antibody for ELISA
Cat No. 21950-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

ELISA and More (1)

A T mutated, AT1, ATA, ataxia telangiectasia mutated, ATC, ATD, ATDC, ATE, ATM, Serine protein kinase ATM, TEL1, TELO1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格价格库存


Planning an IHC experiment? We recommend our IHCeasy ATM Ready-To-Use IHC Kit. ATM primary antibody included.

发表文章中的应用

WBSee 4 publications below

产品信息

21950-1-AP targets ATM in WB, ELISA applications and shows reactivity with human samples.

经测试应用 ELISA Application Description
文献引用应用WB
经测试反应性 human
文献引用反应性human
免疫原 ATM fusion protein Ag15123 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ataxia telangiectasia mutated
别名 A T mutated, AT1, ATA, ataxia telangiectasia mutated, ATC, ATD, ATDC, ATE, ATM, Serine protein kinase ATM, TEL1, TELO1
计算分子量 3056 aa, 351 kDa
GenBank蛋白编号BC007023
基因名称 ATM
Gene ID (NCBI) 472
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ13315
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. It is involved in mitogenic signal transduction, meiotic recombination, detection of DNA damage, and cell cycle control.

发表文章

SpeciesApplicationTitle
humanWB

Toxicol Appl Pharmacol

Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.

Authors - Hui Dong
humanWB

Chem Res Toxicol

PMID: 26451628

Authors - Xiufang Song
humanWB

Tumour Biol

Ataxia-telangiectasia group D complementing gene (ATDC) upregulates matrix metalloproteinase 9 (MMP-9) to promote lung cancer cell invasion by activating ERK and JNK pathways.

Authors - Tang Zhong-Ping ZP
humanWB

Phytomedicine

Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade

Authors - Yifan Lin
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