ATM Polyclonal antibody
ATM Polyclonal Antibody for ELISA
验证数据展示
发表文章中的应用
| WB | See 3 publications below |
产品信息
The immunogen of 21950-1-AP is ATM Fusion Protein expressed in E. coli.
| Tested Applications | ELISA |
| Cited Applications | WB |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Immunogen | ATM fusion protein Ag15123 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | ataxia telangiectasia mutated |
| Synonyms | A T mutated, AT1, ATA, ataxia telangiectasia mutated, ATC, ATD, ATDC, ATE, ATM, Serine protein kinase ATM, TEL1, TELO1 |
| Calculated Molecular Weight | 3056 aa, 351 kDa |
| GenBank Accession Number | BC007023 |
| Gene Symbol | ATM |
| Gene ID (NCBI) | 472 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13315 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. It is involved in mitogenic signal transduction, meiotic recombination, detection of DNA damage, and cell cycle control.
发表文章
| Species | Application | Title |
|---|---|---|
Toxicol Appl Pharmacol Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis. | ||
Tumour Biol Ataxia-telangiectasia group D complementing gene (ATDC) upregulates matrix metalloproteinase 9 (MMP-9) to promote lung cancer cell invasion by activating ERK and JNK pathways. |