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AT-56

AT56 是口服有活性的脂钙蛋白型前列腺素 D 合酶 (L-PGDS) 选择性抑制剂，其IC50=95 μM，Ki=75 μM。它能够特异性地抑制L-PGDS 催化的 PGD2介导的嗜睡或疼痛反应。

CAS号

162640-98-4

分子式

C25H27N5

主要靶点

PGE Synthase|Others

仅限科研使用

Cat No : CM05841

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Synonyms

验证数据展示

  • CAS No.: 162640-98-4

    AT-56
    CAS#: 162640-98-4

产品信息

AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.

CAS号 162640-98-4
分子式 C25H27N5
主要靶点 PGE Synthase|Others
主要通路 免疫与炎症|其他
分子量 397.52
纯度 99.50%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

靶点活性

L-PGDS:95 μM (IC50)|L-PGDS:Ki: 75 μM

溶解度

DMSO:25 mg/mL (62.89 mM)

参考文献

1.Urbanet R, et al. Hypertension. 2015 Jul;66(1):149-57.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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