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验证数据展示

  • WB analysis of human plasma using 22262-1-AP (same clone as 22262-1-PBS)

    WB analysis of human plasma using 22262-1-AP (same clone as 22262-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 22262-1-AP (APOC3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22262-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 22262-1-AP (same clone as 22262-1-PBS)

    IHC staining of human liver using 22262-1-AP (same clone as 22262-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22262-1-AP (APOC3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22262-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 22262-1-AP (same clone as 22262-1-PBS)

    IHC staining of human liver using 22262-1-AP (same clone as 22262-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22262-1-AP (APOC3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22262-1-PBS in a different storage buffer formulation.

Apolipoprotein CIII Polyclonal antibody, PBS Only

Apolipoprotein CIII Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 22262-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

APOC3, Apo CIII, ApoC III, APOCIII, Apo-CIII

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

22262-1-PBS targets Apolipoprotein CIII in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 apolipoprotein C-III
别名 APOC3, Apo CIII, ApoC III, APOCIII, Apo-CIII
计算分子量 11 kDa
观测分子量11 kDa
GenBank蛋白编号NM_000040
基因名称 Apolipoprotein CIII
Gene ID (NCBI) 345
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP02656
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Apolipoprotein CIII (apoCIII) is the most abundant C-apolipoprotein in human and is found on very low density lipoproteins, chylomicrons, and high density lipoproteins (HDL) (PMID: 18408013). ApoCIII inhibits lipoprotein lipase as well as binding of lipoproteins to cell surface heparan sulfate proteoglycans and receptors (PMID: 26228667). ApoC-III has 3 actions that can impair plasma lipoprotein metabolism and lead to hypertriglyceridemia (PMID: 24941081).