验证数据展示
产品信息
18717-1-AP targets ANTXR1 in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | anthrax toxin receptor 1 |
| 别名 | anthrax toxin receptor 1, ANTXR1, ATR, TEM8, Tumor endothelial marker 8 |
| 计算分子量 | 63 kDa |
| GenBank蛋白编号 | NM_032208 |
| 基因名称 | ANTXR1 |
| Gene ID (NCBI) | 84168 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H6X2 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ANTXR1, also named as ATR and TEM8, is type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. It has been shown to be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. It is highly expressed in tumor endothelial cells. The antibody only recognizes the isoform 1 of ANTXR1.