验证数据展示
产品信息
85426-4-PBS targets ALDH1B1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | ALDH1B1 fusion protein Ag7144 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | aldehyde dehydrogenase 1 family, member B1 |
别名 | 242944D1, Aldehyde dehydrogenase 5, Aldehyde dehydrogenase X, mitochondrial, ALDH5, ALDHX |
计算分子量 | 57 kDa |
观测分子量 | 55 kDa |
GenBank蛋白编号 | BC001619 |
基因名称 | ALDH1B1 |
Gene ID (NCBI) | 219 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P30837 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Aldehyde dehydrogenases (ALDHs) belong to a superfamily of NAD(P)+-dependent enzymes, which catalyze the oxidation of endogenous and exogenous aldehydes to their corresponding acids. ALDH1B1 is a mitochondrial ALDH that it is dramatically upregulated in human colonic adenocarcinoma, making it a potential biomarker for human colon cancer.(PMID:21216231). ALDH1B1 is a homotetramer expressed in various adult and fetal human tissues including liver, testis, kidney, skeletal muscle, heart, placenta, brain and lung(PMID:18611112). This antibody is specific to ALDH1B1.