验证数据展示
Planning an IHC experiment? We recommend our IHCeasy AGT Ready-To-Use IHC Kit. AGT primary antibody included.
产品信息
18303-1-AP targets Angiotensin in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| 别名 | AGT, Ang I Angiotensin 2, Ang II Angiotensin 3, Ang III, Angiotensin, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, ANHU, Des Asp[1] angiotensin II, Serpin A8, SERPINA8 |
| 计算分子量 | 53 kDa |
| GenBank蛋白编号 | BC011519 |
| 基因名称 | AGT |
| Gene ID (NCBI) | 183 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P01019 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Angiostatin is a part gene (34-43aa) of Angiotensinogen (Serpin A8, 485aa). In response to lowered blood pressure, the enzyme renin cleaves angiotensin-1 (34-43aa) from angiotensinogen. ACE (angiotensin converting enzyme) then removes a dipeptide to yield the physiologically active peptide angiotensin-2 (34-41aa), the most potent pressor substance known, which helps regulate volume and mineral balance of body fluids. Angiotensin-3 (35-41aa) stimulates aldosterone release.
