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验证数据展示

  • WB analysis using 28323-1-AP (same clone as 28323-1-PBS)

    WB analysis using 28323-1-AP (same clone as 28323-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28323-1-AP (ADRB1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28323-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse lung using 28323-1-AP (same clone as 28323-1-PBS)

    IHC staining of mouse lung using 28323-1-AP (same clone as 28323-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 28323-1-AP (ADRB1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28323-1-PBS in a different storage buffer formulation.

ADRB1 Polyclonal antibody, PBS Only

ADRB1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 28323-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

ADRB1R, B1AR, Beta 1 adrenergic receptor

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

28323-1-PBS targets ADRB1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag28223

Product name: Recombinant human ADRB1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 388-477 aa of NM_000684

Sequence: MQRLLCCARRAARRRHATHGDRPRASGCLARPGPPPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 adrenergic, beta-1-, receptor
别名 ADRB1R, B1AR, Beta 1 adrenergic receptor
计算分子量 51 kDa
观测分子量49 kDa
GenBank蛋白编号NM_000684
基因名称 ADRB1
Gene ID (NCBI) 153
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP08588
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ADRB1 (adrenergic receptor beta 1), a member of the G protein-coupled receptor (GPCR) superfamily, responds to catecholamine stimulation. ADRB1 is the predominant subtype expressed in the heart and mediates increases in inotropy and chronotropy when stimulated. ADRB1 mediates a wide range of cardiovascular physiological responses and has been of great interest to researchers as a therapeutic target for cardiovascular diseases. Moreover, three subtypes of ADRBs (ADRB1, ADRB2, and ADRB3) are encoded by three separate genes (PMID:16636683; 33372534; 33593484).

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