验证数据展示
产品信息
14083-1-AP targets ADAM22 in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag5211 Product name: Recombinant human ADAM22 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 27-342 aa of BC036029 Sequence: QAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDVGGPQLTHVDQASFQVDAFGTSFILDVVLNHDLLSSEYIERHIEHGGKTVEVKGGEHCYYQGHIRGNPDSFVALSTCHGLHGMFYDGNHTYLIEPEENDTTQEDFHFHSVYKSRLFEFSLDDLPSEFQQVNITPSKFILKPRPKRSKRQLRRYPRNVEEETKYIELMIVNDHLMFKKHRLSVVHTNTYAKSVVNMADLIYKDQLKTRIVLVAMETWATDNKFAISENPLITLREFMKYRRDFIKEKSDAVHLFSYVTSVMMYYFF 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ADAM metallopeptidase domain 22 |
| 别名 | ADAM 22, ADAM22, MDC2 |
| 计算分子量 | 342 aa, 40 kDa |
| GenBank蛋白编号 | BC036029 |
| 基因名称 | ADAM22 |
| Gene ID (NCBI) | 53616 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9P0K1 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ADAM22 is a transmembrane protein with an extracellular disintegrin and catalytically inactive metalloproteinase domain that is thought to participate in cell-cell and cell-matrix interactions. It is a component of the Kv1 channel protein complex. ADAM22 is previously reported to regulate synaptic transmission and to be a binding partner of leucine-rich glioma inactivated 1 (Lgi1), which is mutated in autosomal-dominant partial epilepsy with auditory features(PMID: 20089912). It has 5 isoforms produced by alternative splicing. This protein has a signal peptide, a propeptide and 4 glycosylation sites.
