验证数据展示
产品信息
27726-1-PBS targets ABCB4 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag26840 Product name: Recombinant human ABCB4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 628-706 aa of BC042531 Sequence: VNMQTSGSQIQSEEFELNDEKAATRMAPNGWKSRLFRHSTQKNLKNSQMCQKSLDVETDGLEANVPPVSFLKVLKLNKT 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| 别名 | ATP binding cassette sub family B member 4, ATP-binding cassette sub-family B member 4, EC:7.6.2.1, MDR3, P-glycoprotein 3 |
| 计算分子量 | 1286 aa, 142 kDa |
| 观测分子量 | 130-140 kDa |
| GenBank蛋白编号 | BC042531 |
| 基因名称 | ABCB4 |
| Gene ID (NCBI) | 5244 |
| RRID | AB_2918128 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P21439 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ABCB4, also known as MDR3, is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCB4 is expressed on the apical membrane of hepatocytes and functions to transport phosphatidylcholine (PC) from hepatocytes into the bile canaliculus (PMID: 16622704).

