• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Herniarin

Herniarin (Ayapanin) 是一种常见的天然香豆素类化合物，存在于开花植物，具有抗肿瘤的活性。

CAS号

531-59-9

分子式

C10H8O3

主要靶点

Others

仅限科研使用

Cat No : CM00241

Print datasheet

Synonyms

Methyl umbelliferyl ether|Ayapanin|7-甲氧基香豆素|7-Methoxycoumarin|Herniarine

验证数据展示

  • CAS No.: 531-59-9

    Herniarin
    CAS#: 531-59-9

产品信息

Herniarin is a natural coumarin with antitumor effect.

CAS号 531-59-9
分子式 C10H8O3
主要靶点 Others
主要通路 其他
分子量 176.17
纯度 100.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Methyl umbelliferyl ether|Ayapanin|7-甲氧基香豆素|7-Methoxycoumarin|Herniarine

体外活性

Herniarin is cytotoxic to breast carcinoma cell line MCF-7 (IC50: 207.6 μM). Herniarin (100 μM) also induces apoptosis in MCF-7 cells [1]. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin and increases chromatin condensation [2].

溶解度

DMSO:30 mg/mL

参考文献

1.Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.
2.Haghighitalab A, et al. Enhancement of cisplatin cytotoxicity in combination with herniarin in vitro. Drug Chem Toxicol. 2014 Apr;37(2):156-62.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2